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D in the lungs, bacterial numbers do not appreciably increase, and
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Oswaldo Cruz 104(Suppl. 1):252?58. 85. Cunha-Neto, E., et al. 1995. Autoimmunity in Chagas disease cardiopathy: biological relevance of a cardiac myosin-specific epitope crossreactive to an immunodominant Trypanosoma cruzi antigen. Proc. Natl. Acad. Sci. U. S. A. 92:3541?545. 86. Cunningham, D. S., T. E. Brewer, R. E. Kuhn, and W. H. Craig. 1981. Partial characterization of a Trypanosoma cruzi-released decomplementing factor. J. Parasitol. 67:475?80. 87. Cunningham, D. S., W. H. Craig, and R. E. Kuhn. 1978. Reduction of complement levels in mice infected with Trypanosoma cruzi. J. Parasitol. 64:1044?049. 88. Da-Cruz, A. M., et al. 2004. Long-term follow-up of co-infected HIV and Trypanosoma cruzi Brazilian patients. Trans. R. Soc. Trop. Med. Hyg. 98:728?33. 89. da Mata, J. R., E. R. S. Camargos, E. Chiari, and C. R. S. Machado. 2000. Trypanosoma cruzi infection and the rat central nervous system: proliferation of parasites in astrocytes and the brain reaction to parasitism. Brain Res. Bull. 53:153?62. 90. da Matta Guedes, P. M., et al. 2010. IL-17 produced during Trypanosoma cruzi infection plays a central role in regulating [https://britishrestaurantawards.org/members/debt31yacht/activity/286127/ https://britishrestaurantawards.org/members/debt31yacht/activity/286127/] parasite-induced myocarditis. PLoS Negl. Trop. Dis. 4:e604. 91. Daniels, M. D., K. V. Hyland, K. Wang, and D. M. Engman. 2008. Recombinant cardiac myosin fragment induces experimental autoimmune myocarditis via activation of Th1 and Th17 immunity. Autoimmunity 41:490?499. 92. Das, A., M. Banday, and V. Bellofatto. 2008. RNA polymerase transcription machinery in trypanosomes. Eukaryot. Cell 7:429?34. 93. Davila, D. F. 2004. Sympathetic nervous system activation in chagasic patients with congestive heart failure. J. Am. Coll. Cardiol. 43:1723?724. 94. Davila, D. F., J. H. Donis, A. Torres, and J. A. Ferrer. 2004. A modified and ?unifying neurogenic hypothesis can explain the natural history of chronic Chagas heart disease. Int. J. Cardiol. 96:191?95. 95. Davila, D. F., et al. 2008. Beta-adrenergic blockers in chronic systolic heart ?failure secondary to Chagas' disease. Int. J. Cardiol. 128:1?. 96. Davila, D. F., et al. 2008. Anti-muscarinic autoantibodies and vagal mod?ulation in Chagas disease: positive allosteric modulators vs desensitization and downregulation of M2 cardiac acetylcholine receptors. Int. J. Cardiol. 123:328?29. 97. Davila, D. F., T. J. Nunez, R. Odreman, and C. A. de Davila. 2005. Mech?  ?anisms of neurohormonal activation in chronic congestive heart failure: pathophysiology and therapeutic implications. Int. J. Cardiol. 101:343?46. 98. de Alencar, B. C., et al. 2009. Perforin and gamma interferon expression are required for CD4 and CD8 T-cell-dependent protective immunity against a human parasite, Trypanosoma cruzi, elicited by heterologous plasmid DNA prime-recombinant adenovirus 5 boost vaccination. Infect. Immun. 77:4383?395. 99. Deane, M. P., H. L. Lenzi, and A. M. Jansen. 1986. Double development cycle of Trypanosoma cruzi in the opossum. Parasitol. Today 2:146?47. 100. Decottignies, A. 2007. Microhomology-mediated end joining in fission yeast is repressed by pku70 and relies on genes involved in homologous recombination. Genetics 176:1403?415. 101. Deem, S. L., et al. 2009. Health assessment of free-ranging three-banded (Tolypeutes matacus) and nine-banded (Dasypus novemcinctus) armadillos in the Gran Chaco, Bolivia. J. Zoo Wildl. Med.
D in the lungs, bacterial numbers do not appreciably increase, and the infection does not progress to a debilitating and deadly pneumonia. While Pla is necessary for the progression of both bubonic and pneumonic plague, it seems to have opposing contributions to virulence depending on the route of infection. During bubonic plague, Pla is necessary for bacterial dissemination and inhibition of immune cell recruitment, yet does not affect bacterial growth at the local site of infection. In contrast, following intranasal infection, Pla is necessary for outgrowth of the bacteria in the lungs by aiding either growth or [https://www.medchemexpress.com/Darapladib.html Darapladib In stock] survival in this environment, yet is dispensable for dissemination. It remains.
 

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Oswaldo Cruz 104(Suppl. 1):252?58. 85. Cunha-Neto, E., et al. 1995. Autoimmunity in Chagas disease cardiopathy: biological relevance of a cardiac myosin-specific epitope crossreactive to an immunodominant Trypanosoma cruzi antigen. Proc. Natl. Acad. Sci. U. S. A. 92:3541?545. 86. Cunningham, D. S., T. E. Brewer, R. E. Kuhn, and W. H. Craig. 1981. Partial characterization of a Trypanosoma cruzi-released decomplementing factor. J. Parasitol. 67:475?80. 87. Cunningham, D. S., W. H. Craig, and R. E. Kuhn. 1978. Reduction of complement levels in mice infected with Trypanosoma cruzi. J. Parasitol. 64:1044?049. 88. Da-Cruz, A. M., et al. 2004. Long-term follow-up of co-infected HIV and Trypanosoma cruzi Brazilian patients. Trans. R. Soc. Trop. Med. Hyg. 98:728?33. 89. da Mata, J. R., E. R. S. Camargos, E. Chiari, and C. R. S. Machado. 2000. Trypanosoma cruzi infection and the rat central nervous system: proliferation of parasites in astrocytes and the brain reaction to parasitism. Brain Res. Bull. 53:153?62. 90. da Matta Guedes, P. M., et al. 2010. IL-17 produced during Trypanosoma cruzi infection plays a central role in regulating https://britishrestaurantawards.org/members/debt31yacht/activity/286127/ parasite-induced myocarditis. PLoS Negl. Trop. Dis. 4:e604. 91. Daniels, M. D., K. V. Hyland, K. Wang, and D. M. Engman. 2008. Recombinant cardiac myosin fragment induces experimental autoimmune myocarditis via activation of Th1 and Th17 immunity. Autoimmunity 41:490?499. 92. Das, A., M. Banday, and V. Bellofatto. 2008. RNA polymerase transcription machinery in trypanosomes. Eukaryot. Cell 7:429?34. 93. Davila, D. F. 2004. Sympathetic nervous system activation in chagasic patients with congestive heart failure. J. Am. Coll. Cardiol. 43:1723?724. 94. Davila, D. F., J. H. Donis, A. Torres, and J. A. Ferrer. 2004. A modified and ?unifying neurogenic hypothesis can explain the natural history of chronic Chagas heart disease. Int. J. Cardiol. 96:191?95. 95. Davila, D. F., et al. 2008. Beta-adrenergic blockers in chronic systolic heart ?failure secondary to Chagas' disease. Int. J. Cardiol. 128:1?. 96. Davila, D. F., et al. 2008. Anti-muscarinic autoantibodies and vagal mod?ulation in Chagas disease: positive allosteric modulators vs desensitization and downregulation of M2 cardiac acetylcholine receptors. Int. J. Cardiol. 123:328?29. 97. Davila, D. F., T. J. Nunez, R. Odreman, and C. A. de Davila. 2005. Mech? ?anisms of neurohormonal activation in chronic congestive heart failure: pathophysiology and therapeutic implications. Int. J. Cardiol. 101:343?46. 98. de Alencar, B. C., et al. 2009. Perforin and gamma interferon expression are required for CD4 and CD8 T-cell-dependent protective immunity against a human parasite, Trypanosoma cruzi, elicited by heterologous plasmid DNA prime-recombinant adenovirus 5 boost vaccination. Infect. Immun. 77:4383?395. 99. Deane, M. P., H. L. Lenzi, and A. M. Jansen. 1986. Double development cycle of Trypanosoma cruzi in the opossum. Parasitol. Today 2:146?47. 100. Decottignies, A. 2007. Microhomology-mediated end joining in fission yeast is repressed by pku70 and relies on genes involved in homologous recombination. Genetics 176:1403?415. 101. Deem, S. L., et al. 2009. Health assessment of free-ranging three-banded (Tolypeutes matacus) and nine-banded (Dasypus novemcinctus) armadillos in the Gran Chaco, Bolivia. J. Zoo Wildl. Med.