ผลต่างระหว่างรุ่นของ "หน้าหลัก"
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| − | + | N the search interface shown in Figure 7. On the list of controlled | |
| + | N the search interface shown in Figure 7. One of the controlled vocabularies is Anatomy, which has been clicked to open up the list of Anatomy terms in the OCDM. The user has then checked Medial nasal procedure, which causes the search engine to retrieve all these datasets that have been annotated with Medial nasal approach, within this case gene expression data from the developing mouse. A user hunting for information relevant to cleft lip could realize that the left and suitable medial nasal processes are developmental precursors towards the philtrum (Figure 5), that is in turn part of the upper lip and not fused in some sorts of cleft lip. But if the user did not have this expertise, they would not know to click on medial nasal method in the Hub search. Even so, this understanding is present inside the ontology, so we've got utilised the Query Integrator to integrate a query over the ontology with one particular more than the Hub annotated information, allowing the user to begin just with cleft lip and return all these datasets annotated having a developmental precursor of cleft lip. The ontology query initial examines relations like these shown in Figure 6 to decide that Cleft lip has subclass Cleft upper lip, which can be a variation_of Upper lip. The query then examines relations like those shown in Figure five to locate the developmental lineage of Upper lip, returning all structures within this lineage, including the appropriate and left medial nasal approach. This list of precursor structures is then utilised within a second query that searches the Hub database for all those datasets annotated with an Anatomy term which is among these precursor structures. The result, that is only accessible in raw type (and therefore not shown right here) because it's not however integrated with all the Hub search interfaces, would be the set of data annotated with any precursor structures to a structure involved in cleft lip, without having requiring the user to understand what those structures are.Am J Med Genet C Semin Med Genet. Author manuscript; offered in PMC 2014 June 02.NIH-PA Author Manuscript NIH-PA Author Manuscript NIH-PA Author ManuscriptBrinkley et al.PageAlthough the information embodied in this instance is straightforward and likely already known by most craniofacial researchers, this query nonetheless demonstrates the prospective of combining ontological know-how with queries over annotated information. Because the know-how in the OCDM becomes more detailed, and as relevant information grow to be additional precisely annotated, this possible ought to come to be increasingly valuable for discovering information relevant to precise phenotypes, not only from the Hub, but in addition from other web accessible craniofacial information sources. OCDM Viewer The queries presented within the last section will not be best for end customers since the queries and their benefits are only out there in raw type. Having said that, these queries can be accessed by applications that present a clickable user interface, thereby hiding the facts from the query from the user. As a single example of such an application, a basic web-based viewer (obtainable at http://purl.org/sig/ocdm/viewer) displays content in the OCDM. The viewer has been created for two purposes: (1) it exposes the structure and content on the OCDM to members in the craniofacial analysis neighborhood because the OCDM is becoming developed, because feedback is going to be essential to make sure that the OCDM accurately and entirely represents concepts in craniofacial study and in clinical settings; and (2) it serves as a demonstration of how a user interface can retrieve content in the OCDM applying saved q. | ||
รุ่นแก้ไขเมื่อ 05:26, 21 มิถุนายน 2564
N the search interface shown in Figure 7. On the list of controlled N the search interface shown in Figure 7. One of the controlled vocabularies is Anatomy, which has been clicked to open up the list of Anatomy terms in the OCDM. The user has then checked Medial nasal procedure, which causes the search engine to retrieve all these datasets that have been annotated with Medial nasal approach, within this case gene expression data from the developing mouse. A user hunting for information relevant to cleft lip could realize that the left and suitable medial nasal processes are developmental precursors towards the philtrum (Figure 5), that is in turn part of the upper lip and not fused in some sorts of cleft lip. But if the user did not have this expertise, they would not know to click on medial nasal method in the Hub search. Even so, this understanding is present inside the ontology, so we've got utilised the Query Integrator to integrate a query over the ontology with one particular more than the Hub annotated information, allowing the user to begin just with cleft lip and return all these datasets annotated having a developmental precursor of cleft lip. The ontology query initial examines relations like these shown in Figure 6 to decide that Cleft lip has subclass Cleft upper lip, which can be a variation_of Upper lip. The query then examines relations like those shown in Figure five to locate the developmental lineage of Upper lip, returning all structures within this lineage, including the appropriate and left medial nasal approach. This list of precursor structures is then utilised within a second query that searches the Hub database for all those datasets annotated with an Anatomy term which is among these precursor structures. The result, that is only accessible in raw type (and therefore not shown right here) because it's not however integrated with all the Hub search interfaces, would be the set of data annotated with any precursor structures to a structure involved in cleft lip, without having requiring the user to understand what those structures are.Am J Med Genet C Semin Med Genet. Author manuscript; offered in PMC 2014 June 02.NIH-PA Author Manuscript NIH-PA Author Manuscript NIH-PA Author ManuscriptBrinkley et al.PageAlthough the information embodied in this instance is straightforward and likely already known by most craniofacial researchers, this query nonetheless demonstrates the prospective of combining ontological know-how with queries over annotated information. Because the know-how in the OCDM becomes more detailed, and as relevant information grow to be additional precisely annotated, this possible ought to come to be increasingly valuable for discovering information relevant to precise phenotypes, not only from the Hub, but in addition from other web accessible craniofacial information sources. OCDM Viewer The queries presented within the last section will not be best for end customers since the queries and their benefits are only out there in raw type. Having said that, these queries can be accessed by applications that present a clickable user interface, thereby hiding the facts from the query from the user. As a single example of such an application, a basic web-based viewer (obtainable at http://purl.org/sig/ocdm/viewer) displays content in the OCDM. The viewer has been created for two purposes: (1) it exposes the structure and content on the OCDM to members in the craniofacial analysis neighborhood because the OCDM is becoming developed, because feedback is going to be essential to make sure that the OCDM accurately and entirely represents concepts in craniofacial study and in clinical settings; and (2) it serves as a demonstration of how a user interface can retrieve content in the OCDM applying saved q.
