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Al.PageColon cancer and the alpha-bug hypothesisInfection-driven chronic inflammation can promote Al.PageColon cancer and the alpha-bug hypothesisInfection-driven chronic inflammation can promote carcinogenesis in the affected tissues or organs. For instance, chronic Tenidap Purity & Documentation infection with Helicobacter pylori is a major cause of gastric cancer and chronic hepatitis B or C virus infection can lead to liver cancer47. In these and certain other types of cancer, e.g., cervical cancer (human papillomavirus), Burkitt's lymphoma (Epstein-Barr virus), and urinary bladder cancer (Schistosoma hematobium), the oncogenic risk is defined by a specific pathogenic organism. By contrast, colon cancer has not been linked to a single microorganism, although the colonic microbiota is required for induction of chr.