หน้าหลัก

F yeast cells is the generation of iron/sulfur (Fe/S F yeast cells is the generation of iron/sulfur (Fe/S) clusters, which are assembled in proteins destined to mitochondrial, cytosolic, or nuclear compartments (Craig et al., 1999; Lill et al., 1999; Lill and Kispal, 2000). These clusters are especially sensitive to oxidants (Keyer and Imlay, 1996) and liberate free iron that could further reactive oxygen species (ROS) production (Cadenas, 1989). Biogenesis of Fe/S clusters is a conserved process from bacteria to higher eukaryotes (Lill et al., 1999; Lill and Kispal, 2000), although in humans biosynthetic complexes for Fe/S cluster assembly are also found in the cytosol (Tong and Title Loaded From File Rouault, 2000). In S. cerevisiae, synthesis and assembly of Fe/S.